Responsive design - css properties to avoid

I was wondering if there are any properties that impacts negatively responsive design, i have had issues with responsive in particular when using position: absolute, im assuming any properties that are used to take elements out of the normal flow has an influence.

Bootstrap helps a lot when developing responsive layouts, otherwise I always try to stick to Flexbox to position my elements.

As far as other css properties to avoid, I am not sure, however I imagine setting minimum widths or heights that could be larger than the screen size would be an issue