To do what? To defeat Godzilla?
Sure, any two languages can work together. You just need to have a way for them to communicate. Sometimes you can load up another languages code and run it from another using various libraries and interpreters.
Can you be more specific about what you want to do?
I wanted to create a responsive website with a dashboard feature, more like a membership and e-commerce website?
I wanted to use Flask or Django, which one do you recommend for a beginner, Django or Flask?
Sorry, I have never used either. I believe those are backend, for your server.
Think of it this way, imagine a newscaster on the nightly news. You have a pretty person on camera reading the news. That is the frontend, what you see on the screen of your computer. That newscaster has people “serving” him information to read and respond to. Those are the backend, the servers.